PPP1A (PPP1CA) Mouse Monoclonal Antibody [Clone ID: LBI6E5]

PPP1CA

Focal adhesion, Insulin signaling pathway, Long-term potentiation, Oocyte meiosis, Regulation of actin cytoskeleton, Vascular smooth muscle contraction

Full length human recombinant protein of human PPP1CA(NP_001008709) produced in E.coli.

PPP1CA

The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)