« Back
Home /
JIP1 (MAPK8IP1) Mouse Monoclonal Antibody [Clone ID: LBI3A12]

JIP1 (MAPK8IP1) Mouse Monoclonal Antibody [Clone ID: LBI3A12]

Item no.	LBI-AMM19292V
Manufacturer	Leading Biology
Amount	100 ul
Category	Metabolism Antibodies Obesity
Type	Antibody Monoclonal
Format	Liquid
Clone	LBI3A12
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG2b
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	IB1, JIP-1, JIP1, PRKM8IP
Available
Manufacturer - Category	mAbs-V
Manufacturer - Targets	MAPK8IP1
Storage Conditions	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	MAPK signaling pathway
Overview	MAPK8IP1 mouse monoclonal antibody, clone LBI3A12
Immunogen	Full length human recombinant protein of human MAPK8IP1 (NP_005447) produced in HEK293T cell.
Gene Name	mitogen-activated protein kinase 8 interacting protein 1
Symbol	MAPK8IP1
Function	Druggable Genome
Summary	This gene encodes a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes. [provided by RefSeq, May 2011]
Manufacturer - Format	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Storage Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution	WB 1:2000
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	MAPK signaling pathway

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 100 ul

available

Delivery expected until 1/15/2026

Express Delivery: Save 20 days

Compare

Add to wishlist

Get an offer