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Caveolin 1 (CAV1) Mouse Monoclonal Antibody [Clone ID: LBI2C4]

Caveolin 1 (CAV1) Mouse Monoclonal Antibody [Clone ID: LBI2C4]

Item no.	LBI-AMM20853V
Manufacturer	Leading Biology
Amount	100 ul
Category	Neuroscience Metabolism Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Antibodies Lipid & Fatty Acid Transport
Type	Antibody Monoclonal
Format	Liquid
Clone	LBI2C4
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	BSCL3, CGL3, LCCNS, MSTP085, PPH3, VIP21
Available
Manufacturer - Category	mAbs-V
Manufacturer - Targets	CAV1
Storage Conditions	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Focal adhesion, Viral myocarditis
Overview	CAV1 mouse monoclonal antibody, clone LBI2C4
Immunogen	Human recombinant protein fragment corresponding to amino acids 2-104 of human CAV1 (NP_001744) produced in E.coli.
Gene Name	caveolin 1
Symbol	CAV1
Function	Druggable Genome, Transmembrane
Summary	The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1. [provided by RefSeq, Mar 2010]
Manufacturer - Format	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Storage Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution	WB 1:500, IHC 1:500
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Focal adhesion, Viral myocarditis

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 1/15/2026

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