Comparison

JAK3 Mouse Monoclonal Antibody [Clone ID: LBI2B4]

Item no. LBI-AMM20929VCF
Manufacturer Leading Biology
Amount 100 ug
Category
Type Antibody Monoclonal
Format Lyophilized
Clone LBI2B4
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1
Conjugate/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK
Available
Manufacturer - Category
mAbs-V
Manufacturer - Targets
JAK3
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research
Chemokine signaling pathway, Jak-STAT signaling pathway, Primary immunodeficiency
Overview
Carrier-free (BSA/glycerol-free) JAK3 mouse monoclonal antibody, clone LBI2B4
Immunogen
Human recombinant protein fragment corresponding to amino acids 811-1124 of human JAK3 (NP_000206) produced in E.coli.
Gene Name
Homo sapiens Janus kinase 3 (JAK3), mRNA.
Symbol
JAK3
Function
Druggable Genome, Protein Kinase
Summary
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008]
Manufacturer - Format
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Dilution
WB 1:500
Purification
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway
Chemokine signaling pathway, Jak-STAT signaling pathway, Primary immunodeficiency

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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