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B7H3 (CD276) Mouse Monoclonal Antibody [Clone ID: LBI1A10]

B7H3 (CD276) Mouse Monoclonal Antibody [Clone ID: LBI1A10]

Item no.	LBI-AMM21149VCF
Manufacturer	Leading Biology
Amount	100 ug
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Melanoma Sarcoma Mesothelioma
Type	Antibody Monoclonal
Format	Lyophilized
Clone	LBI1A10
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	4Ig-B7-H3, B7-H3, B7H3, B7RP-2
Available
Manufacturer - Category	mAbs-V
Manufacturer - Targets	CD276
Storage Conditions	Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Cell adhesion molecules (CAMs)
Overview	Carrier-free (BSA/glycerol-free) CD276 mouse monoclonal antibody, clone LBI1A10
Immunogen	Full length human recombinant protein of human CD276 (NP_079516) produced in HEK293T cell.
Gene Name	Homo sapiens CD276 molecule (CD276), transcript variant 2, mRNA.
Symbol	CD276
Function	Druggable Genome, Transmembrane
Summary	The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].
Manufacturer - Format	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Buffer	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Dilution	WB 1:500-1000, FLOW 1:100
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Cell adhesion molecules (CAMs)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/15/2026

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