Comparison

IL2 Receptor alpha (IL2RA) Mouse Monoclonal Antibody [Clone ID: LBI1A6]

Item no. LBI-AMM21193V
Manufacturer Leading Biology
Amount 100 ul
Category
Type Antibody Monoclonal
Format Liquid
Clone LBI1A6
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG2a
Conjugate/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias CD25, IDDM10, IL2R, IMD41, p55, TCGFR
Available
Manufacturer - Category
mAbs-V
Manufacturer - Targets
IL2RA
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research
Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Jak-STAT signaling pathway
Overview
IL2RA mouse monoclonal antibody, clone LBI1A6
Immunogen
Full length human recombinant protein of human IL2RA (NP_000408) produced in HEK293T cell.
Gene Name
interleukin 2 receptor subunit alpha
Symbol
IL2RA
Function
Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Summary
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]
Manufacturer - Format
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration
1 mg/ml
Storage Buffer
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution
FLOW 1:100
Purification
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway
Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Jak-STAT signaling pathway

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
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