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Desmin (DES) Mouse Monoclonal Antibody [Clone ID: UMLBI166]

Desmin (DES) Mouse Monoclonal Antibody [Clone ID: UMLBI166]

Item no.	LBI-AMM21850V
Manufacturer	Leading Biology
Amount	100 ul
Category	Antibodies Cell Biology Cytoskeleton Intermediate filaments
Type	Antibody Monoclonal
Format	Liquid
Clone	UMLBI166
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CSM1, CSM2, LGMD2R
Available
Manufacturer - Category	mAbs-V
Manufacturer - Targets	DES
Storage Conditions	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)
Overview	Desmin mouse monoclonal antibody, clone UMLBI166
Immunogen	Full length human recombiant protein of human DES(NP_001918) produced in E.coli.
Gene Name	Homo sapiens desmin (DES), transcript variant 1, mRNA.
Symbol	DES
Function	Druggable Genome
Summary	This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq, Jul 2008]
Manufacturer - Format	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5~1.0 mg/ml (Lot Dependent)
Storage Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution	IHC 1:200
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 1/15/2026

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