Comparison

GBA Mouse Monoclonal Antibody [Clone ID: UMLBI171]

Item no. LBI-AMM21909V
Manufacturer Leading Biology
Amount 100 ul
Category
Type Antibody Monoclonal
Format Liquid
Clone UMLBI171
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG2a
Conjugate/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias GBA1, GCB, GLUC
Available
Manufacturer - Category
mAbs-V
Manufacturer - Targets
GBA
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research
Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism
Overview
GBA mouse monoclonal antibody, clone UMLBI171
Immunogen
Human recombinant protein fragment corresponding to amino acids 40-315 of human GBA (NP_000148) produced in E.coli.
Gene Name
Homo sapiens glucosylceramidase beta (GBA), transcript variant 1, mRNA.
Symbol
GBA
Function
Druggable Genome
Summary
This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]
Manufacturer - Format
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration
0.5~1.0 mg/ml (Lot Dependent)
Storage Buffer
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution
IHC 1:100~200
Purification
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway
Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
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