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MSH2 Mouse Monoclonal Antibody [Clone ID: UMLBI259]

MSH2 Mouse Monoclonal Antibody [Clone ID: UMLBI259]

Item no.	LBI-AMM21993V
Manufacturer	Leading Biology
Amount	100 ul
Category	Oncology Antibodies By Cell Type Carcinoma Glioma Hematology Lymphoma Myeloma Melanoma Sarcoma Mesothelioma
Type	Antibody Monoclonal
Format	Liquid
Clone	UMLBI259
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG2b
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	COCA1, FCC1, hMSH2, HNPCC, HNPCC1, LCFS2, MMRCS2
Available
Manufacturer - Category	mAbs-V
Manufacturer - Targets	MSH2
Storage Conditions	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Colorectal cancer, Mismatch repair, Pathways in cancer
Overview	MSH2 mouse monoclonal antibody, clone UMLBI259
Immunogen	Human recombinant protein fragment corresponding to amino acids 1-304 of human MSH2 (NP_000242) produced in E.coli.
Gene Name	Homo sapiens mutS homolog 2 (MSH2), transcript variant 1, mRNA.
Symbol	MSH2
Function	Druggable Genome, Stem cell - Pluripotency
Summary	This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Manufacturer - Format	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5~1.0 mg/ml (Lot Dependent)
Storage Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution	IHC 1:2400
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Colorectal cancer, Mismatch repair, Pathways in cancer

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 1/15/2026

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