Arginase inhibitor 1

Item no.	HY-15775-10mM
Manufacturer	MedChem Express
CASRN	1345808-25-4
Amount	10 mM/1 mL
Quantity options	100 mg 10 mM/1 mL 10 mg 1 mg 50 mg 5 mg
Category	Oncology Neuroscience Neuroinflammation Molecular Targets for Neuroscience Targets for Rodent Neurosciences Inhibitors & Compound Libraries Small Molecules By Organ Hepatic Cancer
Type	Inhibitors
Specific against	other
Purity	98.0
Citations	[1]Van Zandt MC, et al. Discovery of (R)-2-amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic acid and congeners as highly potentinhibitors of human arginases I and II for treatment of myocardial reperfusion injury. J Med Chem. 2013 Mar 28;56(6):2568-80.
Smiles	O=C(O)[C@@](CCN1CCCCC1)(N)CCCCB(O)O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1345808-25-4
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Arginase
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	286.18
Product Description	Arginase inhibitor 1 is a potent inhibitor of human arginases I and II with IC50s of 223 and 509 nM, respectively.
Manufacturer - Research Area	Cancer
Solubility	DMSO : ≥ 48 mg/mL\|H2O : ≥ 30 mg/mL
Manufacturer - Pathway	Immunology/Inflammation; Metabolic Enzyme/Protease
Clinical information	No Development Reported

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