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Petadeferitrin

Petadeferitrin

Item no.	HY-16912-10mM
Manufacturer	MedChem Express
CASRN	911714-45-9
Amount	10 mM/1 mL
Quantity options	100 mg 10 mM/1 mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.71
Citations	[1]Bergeron RJ, et al. Substituent effects on desferrithiocin and desferrithiocin analogue iron-clearing and toxicity profiles. J Med Chem. 2012 Aug 23;55(16):7090-103.\|[2]Basu S, et al. Understanding the intricacies of iron overload associated with β-thalassemia: a comprehensive review[J]. Thalassemia Reports, 2023, 13(3): 179-194.\|[3]Taher A T, et al. Safety and pharmacokinetics of the oral iron chelator SP‐420 in β‐thalassemia[J]. American Journal of Hematology, 2017, 92(12): 1356-1361.
Smiles	O=C([C@]1(C)N=C(C2=CC=C(OCCOCCOC)C=C2O)SC1)O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	SP-420
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Targets	Ferroptosis
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	355.41
Product Description	Petadeferitrin (SP-420) is a tridentate iron chelator belonging to the class of iron chelators, with orally activity. Petadeferitrin can be used in research related to β-thalassemia[1][2][3].
Manufacturer - Research Area	Metabolic Disease
Solubility	DMSO: ≥ 38 mg/mL
Manufacturer - Pathway	Apoptosis
Clinical information	Phase 2

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HY-16912-10mM-safety-datasheet.pdf