MI-2-2

Item no.	DCC-DC20449-5mg
Manufacturer	DCChemicals
CASRN	1454920-20-7
Amount	5 mg
Category	Reagents & Chemicals Molecules
Type	Inhibitors
Specific against	other
Purity	>98%
Smiles	CC1(C)SC(N2CCN(C3C4C=C(CC(F)(F)F)SC=4N=CN=3)CC2)=NC1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1454920-20-7
Similar products	1454920-20-7
Available
Manufacturer - Applications	MI-2-2 is a potent inhibitor of the menin-MLL interaction that binds to menin with low nanomolar affinity (Kd=22 nM); inhibits the interaction of menin with MLL-AF9 in HEK293 cells in a dose-dependent manner with 4-fold potentcy improvement over MI-2; suppresses growth of MLL-AF9–transformed BMCs; causes MV4:11 cells growth inhibition of with GI50 of 3 uM.
Molecular Weight	415, 497

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5 mg

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Delivery expected until 1/1/2026

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