Comparison

Glabrescione B

Item no. DCC-DC21049-5mg
Manufacturer DCChemicals
CASRN 65893-94-9
Amount 5 mg
Category
Type Inhibitors
Applications other, IV
Specific against other
Purity >98%
Smiles O=C1C(C2=CC=C(OC/C=C(C)/C)C(OC/C=C(C)/C)=C2)=COC3=CC(OC)=CC(OC)=C13
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias 65893-94-9
Similar products 65893-94-9
Available
Manufacturer - Applications
Glabrescione B (GlaB) is a small molecule binding to Gli1 zinc finger and impairing Gli1 activity by interfering with Gli1/DNA interaction, inhibits Hh signaling by impairing Gli1 function; inhibits the growth of Hedgehog-dependent tumor cells in vitro and in vivo, inhibits Gli1-dependent growth of cerebellum-derived normal progenitors; inhibits the growth of Gli-dependent medulloblastoma and tumor-derived stem-like cells; inhibits the growth of Gli-dependent basal cell carcinoma in vitro and in vivo.
Molecular Weight
450, 52

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 5 mg
Available: In stock
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