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tenovin-1

tenovin-1

Item no.	V0016-5mg
Manufacturer	InvivoChem LLC
CASRN	380315-80-0
Amount	5 mg
Quantity options	100 mg 10 mg 1 g 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	380315-80-0
Available
Description	InvivoChem Cat #:V0016CAS #:380315-80-0Purity >=98% Description: Tenovin-1, a small molecule compound discovered by a cell-based screen, is a novel and potent activator of p53 that protects against MDM2-mediated p53 degradation. It acts by inhibiting the protein-deacetylating activities of SirT1 and SirT2, and elevating the levels of p53 protein, p53-downstream target p21CIP/WAF1 protein and mRNA and protects p53 from mdm2-mediated degradation with little impact on p53 synthesis. Reference: Cancer Cell. 2008 May; 13(5):454-63.
Molecular Weight (MW)	369.48
Formula	C20H23N3O2S
CAS No.	380315-80-0
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 74 mg/mL (200.28 mM)
	Water:< 1 mg/mL (slightly soluble or insoluble)
	Ethanol:< 1 mg/mL
Solubility (In vivo)	15% Captisol: 15 mg/mL
Synonyms	Tenovin-1; Tenovin1; Tenovin 1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5 mg

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Delivery expected until 9/4/2025

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