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1-azakenpaullone

1-azakenpaullone

Item no.	V0224-5mg
Manufacturer	InvivoChem LLC
CASRN	676596-65-9
Amount	5mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	676596-65-9
Available
Description	InvivoChem Cat #:V0224CAS #:676596-65-9Purity >=98% Description: 1-Azakenpaullone (1-Akp), an analog of kenpaullone, is a novel, ATP-competitive and selective inhibitor of GSK-3beta (glycogen synthase kinase 3beta) with potential antidiabetic and neuroprotective activities. It inhibits GSK-3beta with an IC50 of 18 nM, and exhibits > 100-fold selectivity for GSK-3beta over CDK1/cyclin B and CDK5/p25. Description: Description: References:J Med Chem. 2008 Apr 10; 51(7):2196-207; Eur J Biochem. 2000 Oct; 267(19):5983-94; J Biol Chem. 2007 Apr 20; 282(16):12030-7. References:References:

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Amount: 5mg

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Delivery expected until 7/3/2025

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