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2-methoxyestradiol-2-meoe2

2-methoxyestradiol-2-meoe2

Item no.	V0294-50mg
Manufacturer	InvivoChem LLC
CASRN	362-07-2
Amount	50mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	362-07-2
Available
Description	InvivoChem Cat #:V0294CAS #:362-07-2Purity >=98% Description: 2-Methoxyestradiol (2-MeOE2, NSC-659853, 2-ME2; 2-ME), an endogenous/natural metabolite of estradiol 17beta-estradiol (E2), is a potent inhibitor of tubulin with potential anticancer activity. It also acts as a blocker of HIF-1alpha nuclear accumulation and HIF-transcriptional activity, an inhibitor of angiogenesis as well as an inducer of apoptosis. As an inhibitor of microtubule assembly, it inhibits the polymerization of tubulin and interferes with mitotic spindle dynamics which leads to the blockage of mitosis of human cancer cells. Description:Description: 2-Methoxyestradiol (2-MeOE2, NSC-659853, 2-ME2; 2-ME), an endogenous/natural metabolite of17beta-estradiol (E2), is a potent inhibitor of tubulin with potential anticancer activity. It also acts as a blocker of HIF-1alpha nuclear accumulation and HIF-transcriptional activity, an inhibitor of angiogenesis as well as an inducer of apoptosis. As an inhibitor of microtubule assembly, it inhibits the polymerization of tubulin and interferes with mitotic spindle dynamics which leads to the blockage of mitosis of human cancer cells. an inhibitor of angiogenesis inhibitor of References: Steroids. 2002; 67(13-14):1079-89; Carcinogenesis. 2000; 21(4):735-40; Cancer Res. 2006; 66(24):11991-7. References: References:

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Amount: 50mg

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Delivery expected until 7/3/2025

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