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Azacitidine (Ladakamycin; 5-AzaC)

Azacitidine (Ladakamycin; 5-AzaC)

Item no.	V0404-2g
Manufacturer	InvivoChem LLC
CASRN	320-67-2
Amount	2 g
Quantity options	100 mg 1 g 250 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0404CAS #:320-67-2Purity >=98% Description: 5-Azacytidine (5AzaC; Ladakamycin; U-18496; Vidaza; Mylosar; 5-AzaC) is an FDA approved anticancer drug bearing a pyrimidine nucleoside core and belongs to cytosine class of antimetabolites. It acts as a DNA methyl transferase (DNMT) inhibitor. Description: References: Oncogene. 2002 Aug 12; 21(35):5483-95; J Biol Chem. 1982 Feb 25; 257(4):2041-8. References: Publications Citing Use of InvivoChem Azacitidine (Ladakamycin; 5-AzaC): Nature. 2021 Aug 25. doi: 10.1038/s41586-021-03850-3.
Molecular Weight (MW)	244.2
Formula	C8H12N4O5
CAS No.	320-67-2
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 48 mg/mL (196.6 mM)
	Water:< 1 mg/mL
	Ethanol:< 1 mg/mL
Solubility (In vivo)	30% propylene glycol, 5% Tween 80, 65% D5W: 30 mg/mL
Synonyms	Synonym: Vidaza; Abbreviations: 5AC; 5AZC. U 18496; U18496; 5-azacytidine; azacytidine; U-18496; ladakamycin. US brand names: Mylosar; Chemical Name: 4-amino-1-((2R, 3R, 4S, 5R)-3, 4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1, 3, 5-triazin-2(1H)-one SMILES Code: O=C1N([CH]2O[CH](CO)[CH](O)[CH]2O)C=NC(N)=N1

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Amount: 2 g

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