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Description: UNC1215 (UNC-1215) is a potent and selective antagonist of L3MBTL3, a member of the MBT (malignant brain tumor) family of methyllysine (Kme) reading domain, with potential antineoplastic activity. It inhibits L3MBTL3 with an IC50 of 40 nM and a Kd of 120 nM.
References: Nat Chem Biol. 2013 Mar; 9(3):184-91.
UNC-1215, UNC 1215, UNC1215
Chemical Name: (2-(phenylamino)-1, 4-phenylene)bis((4-(pyrrolidin-1-yl)piperidin-1-yl)methanone)
InChi Key: PQOOIERVZAXHBP-UHFFFAOYSA-N
InChi Code: InChI=1S/C32H43N5O2/c38-31(36-20-12-27(13-21-36)34-16-4-5-17-34)25-10-11-29(30(24-25)33-26-8-2-1-3-9-26)32(39)37-22-14-28(15-23-37)35-18-6-7-19-35/h1-3, 8-11, 24, 27-28, 33H, 4-7, 12-23H2
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