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Skepinone-L (CBS3830)

Skepinone-L (CBS3830)

Item no.	V0486-5mg
Manufacturer	InvivoChem LLC
CASRN	1221485-83-1
Amount	5 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1221485-83-1
Available
Description	InvivoChem Cat #:V0486CAS #:1221485-83-1Purity >=98% Description: Skepinone-L (CBS-3830; CBS3830) is a novel, potent, selective and ATP-competitive inhibitor p38alpha-MAPK with potential anti-inflammatory activity. It inhibits p38alpha-MAPK with an IC50 of 5 nM. Description: References: Nat Chem Biol. 2011 Dec 25; 8(2):141-3; Cell Physiol Biochem. 2013; 31(6):914-24. References:
Molecular Weight (MW)	425.42
Formula	C24H21F2NO4
CAS No.	1221485-83-1
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 85 mg/mL (199.8 mM)
	Water: < 1 mg/mL
	Ethanol: 85 mg/mL (199.8 mM)
Solubility (In vivo)	0.5% methylcellulose: 30 mg/mL
Synonyms	Synonym: CBS3830; CBS-3830; CBS 3830; Skepinone-L Chemical Name: 2-[(2, 4-difluorophenyl)amino]-7-[(2R)-2, 3-dihydroxypropoxy]-10, 11-dihydro-5H-dibenzo[a, d]cyclohepten-5-one InChi Key: HXMGCTFLLWPVFM-GOSISDBHSA-N InChi Code: InChI=1S/C24H21F2NO4/c25-16-4-8-23(22(26)10-16)27-17-5-7-20-15(9-17)2-1-14-3-6-19(11-21(14)24(20)30)31-13-18(29)12-28/h3-11, 18, 27-29H, 1-2, 12-13H2/t18-/m1/s1 SMILES Code: O=C1C2=CC=C(NC3=CC=C(F)C=C3F)C=C2CCC4=CC=C(OC[CH](O)CO)C=C14

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Amount: 5 mg

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Delivery expected until 9/4/2025

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