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PF-04929113 (SNX-5422)

PF-04929113 (SNX-5422)

Item no.	V0890-5mg
Manufacturer	InvivoChem LLC
CASRN	908115-27-5
Amount	5 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	908115-27-5
Available
Description	InvivoChem Cat #:V0890CAS #:908115-27-5 Purity >=98% Description: PF-04929113 (SNX-5422; PF04929113; PF-4929113) is a potent and selective inhibitor of heat shock protein 90 (HSP90) with potential antineoplastic activity. It inhibits HSP90 with a Kd of 41 nM. PF 04929113 exhibits excellent in vivo antitumor efficacy in fox chase SCID mice bearing MM.1S cells. Description:ox chase SCID mice bearing MM.1S cells. References: J Med Chem. 2009; 52(14):4288-305; Blood. 2009; 113(4):846-55; Clin Cancer Res. 2011; 17(8):2301-13. References: Related CAS: 1173111-67-5 (mesylate); 908115-27-5 (free base);
Molecular Weight (MW)	521.53
Formula	C25H30F3N5O4
CAS No.	908115-27-5 (free base);
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 5 mg/mL (9.6 mM)
	Water: < 1 mg/mL
	Ethanol: 3 mg/mL (5.2 mM)
Solubility (In vivo)	0.5% CMC+0.25% Tween 80: 25mg/mL
Synonyms	SNX-5422; PF 4929113; PF04929113; PF 04929113; SNX5422; SNX 5422; PF-04929113; PF4929113; PF-4929113;

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5 mg

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Delivery expected until 9/4/2025

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