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methazolamide

methazolamide

Item no.	V0900-10g
Manufacturer	InvivoChem LLC
CASRN	554-57-4
Amount	10g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0900CAS #:554-57-4Purity >=98% Description: Methazolamide (Neptazaneat; Naptazane; CL-8490; CL8490) is a highly potent and selective inhibitor of carbonic anhydrase (CAI) with important biological activity. It inhibits the isoforms of CA such as hCA I, hCA II and bCA IV with Ki of 50 nM, 14 nM and 36 nM, respectively. Methazolamide is used to glaucoma (to lower the intraocular pressure inside the eyes). Description: References: Bioorg Med Chem Lett. 2003; 13(5):841-5; Am J Physiol Regul Integr Comp Physiol. 2009; 297(3):R648-54. References:
Molecular Weight (MW)	236.27
Formula	C5H8N4O3S2
CAS No.	554-57-4
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 47 mg/mL (198.9 mM)
	Water: < 1 mg/mL
	Ethanol: 3 mg/mL (12.7 mM)
SMILES	CC(/N=C1SC(S(=O)(N)=O)=NN/1C)=O
Synonyms	Methenamide; Neptazaneat; Naptazane; CL 8490; Methazolamide; Neptazane; N Methylacetazolamide; N-Methylacetazolamide; CL8490; CL-8490

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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