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Description: Atomoxetine HCl (formerly LY139603; LY-139603; Tomoxetine; Strattera; Tomoxetina; Tomoxetinum), the hydrochloride salt of Atomoxetine, is a potent and selective norepinephrine (NE) transporter/reuptate inhibitor that has been used for treating attention-deficit hyperactivity disorder (ADHD). It inhibits norepinephrine (NE) transporter/reuptate with a Ki of 5 nM, and exhibits 15- and 290-fold lower affinity for human 5-HT and DA transporters. Atomoxetine was approved for the treatment of ADHD.
References: Neuropsychopharmacology. 2002 Nov; 27(5):699-711; J Pharmacol Exp Ther. 1985 Jan; 232(1):139-43.
Related CAS: 83015-26-3 (free)
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