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tropisetron-hcl-sdz-ics-930-hcl

tropisetron-hcl-sdz-ics-930-hcl

Item no.	V1035-250mg
Manufacturer	InvivoChem LLC
CASRN	105826-92-4
Amount	250mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	105826-92-4
Available
Description	InvivoChem Cat #:V1035CAS #:105826-92-4Purity >=98% Description: Tropisetron HCl (Navoban; ICS-205930; ICS 205-930), the hydrochloride salt of Tropisetron which is an anti-emetic drug, is a novel, potent and selective 5-HT3 receptor antagonist and alpha7-nicotinic receptor agonist that has been approved for the treatment of chemotherapy-induced nausea and vomiting. Tropisetron is a high affinity ligand for both th alpha7 nAChR and 5HT3R. Tropisetron has very low affinity for the other nicotinic subtypes tested. Description: References: Bioorg Med Chem Lett. 2001 Feb 12; 11(3):319-21; Psychopharmacology (Berl). 2005 Nov; 183(1):13-9. References: Related CAS: 89565-68-4 (free base) CAS:CAS: 89565-68-4 (free base)
Molecular Weight (MW)	320.81
Formula	C17H20N2O2.HCl
CAS No.	105826-92-4
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 35 mg/mL (109.1 mM)
	Water: 46 mg/mL (143.4 mM)
	Ethanol: < 1 mg/mL
Other info	Chemical Name: (1R, 5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 1-methyl-1H-indole-3-carboxylate hydrochloride SMILES: O=C(C1=CN(C)C2=C1C=CC=C2)OC3C[CH](N4C)CC[CH]4C3.[H]Cl
Synonyms	Trade name Navoban; ICS-205930; ICS 205-930; Tropisetron; ICS 205930; ICS205930; ICS 205-930; ICS-205-930; Tropisetron HCl;

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Amount: 250mg

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