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Niflumic acid

Niflumic acid

Item no.	V1064-500mg
Manufacturer	InvivoChem LLC
CASRN	4394-00-7
Amount	500 mg
Quantity options	10 g 1 g 25 g 2 g 50 g 5 g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	4394-00-7
Available
Description	InvivoChem Cat #:V1064CAS #:4394-00-7Purity >=98% Description: Niflumic acid (Flunir, Donalgin, Niflactol, Niflugel, Nifluril) is a potent inhibitor of cyclooxygenase-2 (COX-2) enzyme with potential anti-inflammatory and analgesic activity. It is an approved medication used for joint and muscular pain as well as rheumatoid arthritis. Niflumic acid acts an inhibitor of COX (cyclooxygenase-2) enzyme, also a Ca2+-activated Cl- channel blocker. In experimental biology, it has been employed to inhibit chloride channels. Niflumic acid has also been reported to act on GABA-A and NMDA channels and to block T-type calcium channels. Description: References: Mol Pharmacol. 1990 May; 37(5):720-4; FEBS Lett. 1990 Jul 30; 268(1):79-82. References:
Molecular Weight (MW)	282.22
Formula	C13H9F3N2O2
CAS No.	4394-00-7
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 56 mg/mL (198.4 mM)
	Water:< 1 mg/mL
	Ethanol: < 1 mg/mL
Other info	Chemical Name: 2-[3-(trifluoromethyl)anilino]pyridine-3-carboxylic acid InChi Key: JZFPYUNJRRFVQU-UHFFFAOYSA-N InChi Code: InChI=1S/C13H9F3N2O2/c14-13(15, 16)8-3-1-4-9(7-8)18-11-10(12(19)20)5-2-6-17-11/h1-7H, (H, 17, 18)(H, 19, 20) SMILES Code: O=C(C1=CC=CN=C1NC2=CC=CC(C(F)(F)F)=C2)O
Synonyms	Flunir, Niflactol, Niflugel, Niflumic Acid, Donalgin, Nifluril

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Amount: 500 mg

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