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triflusal-ur1501

triflusal-ur1501

Item no.	V1067-5mg
Manufacturer	InvivoChem LLC
CASRN	322-79-2
Amount	5 mg
Quantity options	100 mg 10 mg 1 g 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	322-79-2
Available
Description	InvivoChem Cat #:V1067CAS #:322-79-2 Purity >=98% Description: Triflusal (formerly UR1501; Disgren, Grendis, Aflen, Triflux), a platelet aggregation inhibitor and a salicylate analog, acts by irreversibly inhibiting the production of thromboxane-B2 in platelets via acetylating the enzyme COX-1/cycloxygenase-1. The main metabolite of Triflusal is HTB, which preserves 6-keto-PGF1alpha synthesis in porcine aortic endothelial cells (PAEC) cells without a significant decline for up to 24 h even at the higher concentration. Triflusal at 10 mM, 100 mM and 1 M decreases LDH efflux in rat brain slices after anoxia/reoxygenation by 24%, 35% and 49% respectively. Triflusal also reduces inducible NO synthase activity by 18%, 21% and 30%. Description: References: J Thromb Haemost. 2008 Aug; 6(8):1385-92; Eur J Clin Invest. 2000 Sep; 30(9):811-7. References:
Molecular Weight (MW)	248.16
Formula	C10H7F3O4
CAS No.	322-79-2
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 50 mg/mL (201.5 mM)
	Water: < 1 mg/mL
	Ethanol: 50 mg/mL (201.5 mM)
Other info	Chemical Name: 2-acetyloxy-4-(trifluoromethyl)benzoic acid InChi Key: RMWVZGDJPAKBDE-UHFFFAOYSA-N InChi Code: InChI=1S/C10H7F3O4/c1-5(14)17-8-4-6(10(11, 12)13)2-3-7(8)9(15)16/h2-4H, 1H3, (H, 15, 16) SMILES Code: O=C(O)C1=CC=C(C(F)(F)F)C=C1OC(C)=O
Synonyms	UR-1501; Triflusal, Disgren, UR1501; UR 1501; Grendis, Aflen, Triflux

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Amount: 5 mg

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