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Description: Mefenamic Acid (CI-473; CN-35355; CI 473; CN 35355; Mefenamic Acid; Ponstel; Parkemed; Coslan), a nonsteroidal anti-inflammatory drug (NSAID), is potent, nonselective, competitive inhibitor of the enzymes COX-1 and COX-2 with anti-inflammatory activity. Mefenamic acid displays a wide range of biological acitivity such as anti-inflammatory, analgesic, and antipyretic properties. It also demonstrated potent anti-proliferative activity in vitro against colorectal cancer cells.
References: J Ethnopharmacol. 2015 Jul 21; 170:106-16; Complement Ther Clin Pract. 2016 Feb; 22:12-5.
Chemical Name: 2-(2, 3-dimethylanilino)benzoic acid
InChi Key: HYYBABOKPJLUIN-UHFFFAOYSA-N
InChi Code: InChI=1S/C15H15NO2/c1-10-6-5-9-13(11(10)2)16-14-8-4-3-7-12(14)15(17)18/ h3-9, 16H, 1-2H3, (H, 17, 18)
SMILES: c1(c(cccc1)C(=O)O)Nc1c(c(ccc1)C)C
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