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carprofen

carprofen

Manufacturer	InvivoChem LLC
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
Amount	100mg
Item no.	V1074-100mg
CASRN	53716-49-7
eClass 6.1	32160405
eClass 9.0	32160490
Available
Description	InvivoChem Cat #:V1074CAS #:53716-49-7Purity >=98% Description: Carprofen (Rimadyl; Ro-205720; C 5720; quellin; Novox; Imafen; Rovera), a nonsteroid anti-inflammatory drug (NSAID), is a potent and multi-target FAAH/COX inhibitor with potential anti-inflammatory activity. It inhibits COX-2, COX-1 and FAAH with IC50s of 3.9 uM, 22.3 uM and 78.6 uM, respectively. Veterinarians prescribe it as a supportive treatment for various conditions in animals, is a COX2 inhibitor that inhibits canine COX2 with IC50 of 30 nM. Carprofen (S and R stereoisomers) inhibits canine COX2 with IC50 of 0.102 microM for the racemic mixture, the inhibition is primarily attributable to the S enantiomer (IC50, 0.0371 microM), which is approximately 200-fold more potent than the R enantiomer (IC50, 5.97 microM). It acts as a multi-target FAAH/COX inhibitor, with IC50s of 3.9 uM, 22.3 uM and 78.6 uM for COX-2, COX-1 and FAAH, respectively. Description:a pote. References: Am J Vet Res. 1998 Nov; 59(11):1441-6; Vet Surg. 1998 Nov-Dec; 27(6):568-82. References:
Molecular Weight (MW)	273.71
Formula	C15 H12ClNO2
CAS No.	53716-49-7
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 55 mg/mL (200.9 mM)
	Water: < 1 mg/mL
	Ethanol: 55 mg/mL (200.9 mM)
Other info	Chemical Name: 2-(6-chloro-9H-carbazol-2-yl)propanoic acid InChi Key: PUXBGTOOZJQSKH-UHFFFAOYSA-N InChi Code: InChI=1S/C15H12ClNO2/c1-8(15(18)19)9-2-4-11-12-7-10(16)3-5-13(12)17-14(11)6-9/h2-8, 17H, 1H3, (H, 18, 19) SMILES Code: CC(C1=CC2=C(C=C1)C3=C(N2)C=CC(=C3)Cl)C(=O)O
Synonyms	Ro205720; C-5720; C5720; Carprofen; Imadyl; Rimadyl; Ridamyl; Ro 20-5720; Ro 205720; C 5720; Imadyl; quellin; Novox; Imafen; Rovera

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Amount: 100mg

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Delivery expected until 6/6/2024