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Riluzole (RP-54274, PK 26124)

Riluzole (RP-54274, PK 26124)

Item no.	V1078-10g
Manufacturer	InvivoChem LLC
CASRN	1744-22-5
Amount	10 g
Quantity options	100 mg 1 g 250 mg 2 g 500 mg 5 g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1078CAS #:1744-22-5Purity >=98% Description: Riluzole (formerly PK26124, RP54274, RP-54274, PK-26124; Rilutek), an anticonvulsant of the Na+ channel blocker class, is a glutamate release inhibitor with neuroprotective, anticonvulsant, anxiolytic and anesthetic activities. Riluzole has been approved as a medication to treat amyotrophic lateral sclerosis. Riluzole acts by complex mechanism involving inhibition of voltage-dependent Na channels, high-voltage activated Ca and K channels, and inhibition of protein kinase C. It was suggested that this mechanism was involved in antioxidative processes. Description: References: Neurology. 1996 Dec; 47(6 Suppl 4):S233-41; Naunyn-Schmiedeberg's Archives of Pharmacology References:
Molecular Weight (MW)	234.2
Formula	C8H5F3N2OS
CAS No.	1744-22-5
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 47 mg/mL (200.7 mM)
	Water: < 1 mg/mL
	Ethanol: 47 mg/mL (200.7 mM)
Other info	Chemical Name: 6-(trifluoromethoxy)-1, 3-benzothiazol-2-amine InChi Key: FTALBRSUTCGOEG-UHFFFAOYSA-N InChi Code: InChI=1S/C8H5F3N2OS/c9-8(10, 11)14-4-1-2-5-6(3-4)15-7(12)13-5/h1-3H, (H2, 12, 13) SMILES: NC1=NC2=CC=C(OC(F)(F)F)C=C2S1
Synonyms	PK 26124, RP 54274, PK26124, RP54274, RP-54274, PK-26124; Rilutek

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