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Donepezil HCl (E2020)

Donepezil HCl (E2020)

Item no.	V1159-250mg
Manufacturer	InvivoChem LLC
CASRN	120011-70-3
Amount	250 mg
Quantity options	10 g 1 g 2 g 500 mg 5 g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	120011-70-3
Available
Description	InvivoChem Cat #:V1159CAS #:120011-70-3Purity >=98% Description: Donepezil Hydrochloride (E2020; Aricept; E-2020), the hydrochloride salt of Donepezil, is a noncompetitive, specific and potent AChE inhibitor for bAChE and hAChE with antiAlzheimer's disease (AD) effects. It inhibits bAChE and hAChE with IC50s of 8.12 nM and 11.6 nM , respectively. Acetylcholinesterase (AChE) is an enzyme possibly involved in cognitive dysfunction of patients suffering Alzheimer's disease (AD). Description: References: Neuropharmacology. 1999 Jan; 38(1):181-93; CNS Neurosci Ther. 2012 Feb; 18(2):185-7. References: Related CAS #: 120014-06-4 (free base) 120011-70-3 (HCl)
Molecular Weight (MW)	416
Formula	C24H29NO3.HCl
CAS No.	120011-70-3
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: < 1 mg/mL
	Water: 5 mg/mL (12.01 mM)
	Ethanol: < 1 mg/mL
Solubility (In vivo)	30% propylene glycol, 5% Tween 80, 65% D5W: 30mg/mL
Synonyms	E-2020; E2020; Aricept; E 2020; Donepezil HCl

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Amount: 250 mg

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