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AVE 0991

AVE 0991

Item no.	V11927-5mg
Manufacturer	InvivoChem LLC
CASRN	304462-19-9
Amount	5 mg
Quantity options	10 mg 25 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	304462-19-9
Available
Description	InvivoChem Cat #:V11927CAS #:304462-19-9Purity >=98% Description: AVE-0991 is a novel, orally bioactive non-peptide mimic and high affinity agonist of angiotensin-(1-7) with an IC50 of 21 nM. References: 1. WiemerG, et al. AVE 0991, a nonpeptide mimic of the effects ofangiotensin-(1-7) on the endothelium. Hypertension. 2002Dec; 40(6):847-52. 2. PinheiroSV, et al. Nonpeptide AVE 0991 is an angiotensin-(1-7) receptor Masagonist in the mouse kidney. Hypertension. 2004 Oct; 44(4):490-6. 3. FerreiraAJ, et al. The nonpeptide angiotensin-(1-7) receptor Mas agonistAVE-0991 attenuates heart failure induced by myocardial infarction. Am JPhysiol Heart Circ Physiol. 2007 Feb; 292(2):H1113-9. 4. MoJ, et al. AVE 0991 attenuates oxidative stress and neuronal apoptosisvia Mas/PKA/CREB/UCP-2 pathway after subarachnoid hemorrhage in rats.Redox Biol. 2018 Sep 28; 20:75-86. Related CAS: 306288-04-0 (sodium salt); 304462-19-9 (free base)

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