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doxylamine-succinate

doxylamine-succinate

Item no.	V1228-1g
Manufacturer	InvivoChem LLC
CASRN	562-10-7
Amount	1g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1228CAS #:562-10-7Purity >=98% Description: Doxylamine succinate (Decapryn; Unisom; Evigoa D), the succinate salt of Doxylamine, is an antihistamine drug that can be used as monotherapy (short-term sedative) or in combination with other drugs to relieve night-time allergy and cold. It competitively inhibits histamine at H1 receptors with substantial sedative and anticholinergic effects. The effects of doxylamine (as the succinate salt) on microsomal enzyme activity and serum thyroid hormone levels are examined in B6C3F1 mice following dietary exposure for 7 or 15 days (0, 40, 375, 750, or 1500 ppm in diet, expressed as free base doxylamine). Description: References: Toxicol Appl Pharmacol. 1996 Dec; 141(2):584-94. References: Related CAS No. : 1173020-59-1 (Doxylamine D5); 1216840-94-6 (Doxylamine D5 succinate) : 1173020-59-1 (Doxylamine D5); 1216840-94-6 (Doxylamine D5 succinate)
Molecular Weight (MW)	388.46
Formula	C17H22N2O.C4H6O4
CAS No.	562-10-7
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 78 mg/mL (200.8 mM)
	Water: 78 mg/mL (200.8 mM)
	Ethanol:
Solubility (In vivo)	Chemical Name: butanedioic acid; N, N-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine InChi Key: KBAUFVUYFNWQFM-UHFFFAOYSA-N InChi Code: InChI=1S/C17H22N2O.C4H6O4/c1-17(20-14-13-19(2)3, 15-9-5-4-6-10-15)16-11-7-8-12-18-16; 5-3(6)1-2-4(7)8/h4-12H, 13-14H2, 1-3H3; 1-2H2, (H, 5, 6)(H, 7, 8) SMILES Code: CC(C1=CC=CC=C1)(C2=CC=CC=N2)OCCN(C)C.C(CC(=O)O)C(=O)O
Synonyms	Doxylamine Succinate; Decapryn; Unisom; Evigoa D

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