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gabapentin-hcl

gabapentin-hcl

Item no.	V1284-50mg
Manufacturer	InvivoChem LLC
CASRN	60142-95-2
Amount	50mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1284CAS #:60142-95-2Purity >=98% Description: Gabapentin HCl (Neurontin), the hydrochloride salt of gabapentin which is a GABA analogue, is an orally bioavailable and approved medication used to treat seizures and neuropathic pain. Gabapentin is a major inhibitory neurotransmitter that functions by binding to the GABA receptors located in the spinal cord. Gabapentin also binds to a novel site on voltage-sensitive Ca2+ channels. Additionally, Gabapentin demonstrates inhibition of dopamine release from caudate nucleus, prevent neuronal cell death, and is antinociceptive. It is structurally similar to GABA and is reported in various research studies to increase GABA concentrations within the brain. References: J Pharmacol Exp Ther. 1999 Mar; 288(3):1026-30; Br J Pharmacol. 2002 Jan; 135(1):257-65. Related CAS #:60142-95-2 (HCl) 60142-96-3 (free base)
Molecular Weight (MW)	207.7
Formula	C9H17NO2.HCl
CAS No.	60142-95-2
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: < 1 mg/mL
	Water: 42 mg/mL (202.2 mM)
	Ethanol: < 1 mg/mL
Other info	Chemical Name: 1-(Aminomethyl)cyclohexaneacetic acid HCl InChi Key: XBUDZAQEMFGLEU-UHFFFAOYSA-N InChi Code: InChI=1S/C9H17NO2.ClH/c10-7-9(6-8(11)12)4-2-1-3-5-9; /h1-7, 10H2, (H, 11, 12); 1H SMILES Code: O=C(O)CC1(CN)CCCCC1.[H]Cl
Synonyms	Gabapentin hydrochloride; Neurontin

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Amount: 50mg

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