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flumequine

flumequine

Item no.	V1413-100mg
Manufacturer	InvivoChem LLC
CASRN	42835-25-6
Amount	100 mg
Quantity options	10 g 1 g 250 mg 2 g 500 mg 5 g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	42835-25-6
Available
Description	InvivoChem Cat #:V1413CAS #:42835-25-6Purity >=98% Description: Flumequine (formerly R-802; R 802; R802) is a synthetic quinolone, 1st generation and broad-spectrum chemotherapeutic antibiotic that was once used to treat bacterial infections but has been removed from market. It acts by inhibiting topoisomerase II with an IC50 of 15 uM. Flumequine inhibits eukaryotic topoisomerase II, which is responsible for the double-strand DNA breakage reaction as well as bacterial gyrase, inhibitory effects of FL on topoisomerase II are high relative to the influence on bacterial gyrase. Flumequine has minimum inhibitory concentration (MIC) ranging from 0.06 ug/mL to 32 ug/mL in 12 clinical A. salmonicida isolates. References: Toxicol Sci. 2002 Oct; 69(2):317-21; Antimicrob Agents Chemother. 1995 May; 39(5):1059-64.
Molecular Weight (MW)	261.25
Formula	C14H12FNO3
CAS No.	42835-25-6
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 3 mg/mL (11.5 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Other info	Chemical Name: 7-Fluoro-12-methyl-4-oxo-1-azatricyclo[7.3.1.05, 13]trideca-2, 5, 7, 9(13)-tetraene-3-carboxylic acid InChi Key: DPSPPJIUMHPXMA-UHFFFAOYSA-N InChi Code: InChI=1S/C14H12FNO3/c1-7-2-3-8-4-9(15)5-10-12(8)16(7)6-11(13(10)17)14(18)19/h4-7H, 2-3H2, 1H3, (H, 18, 19) SMILES Code: O=C(C(C1=O)=CN2C(C)CCC3=C2C1=CC(F)=C3)O
Synonyms	R-802; R 802; R802

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Amount: 100 mg

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Delivery expected until 9/4/2025

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