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Description: Mizoribine (also called Bredinin, HE-69; He69; NSC289637; NSC-289637) is an imidazole-based nucleoside isolated from the fungus Penicillium brefeldianum. It can be used as an immunosuppressive agent with an IC50 of 100 uM.
References: Mol Pharmacol. 1992 Apr; 41(4):671-6; Nephrol Dial Transplant. 2005 Aug; 20(8):1573-81.
Chemical Name: 1-((2R, 3R, 4S, 5R)-3, 4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-hydroxy-1H-imidazole-4-carboxamide
InChi Key: HZQDCMWJEBCWBR-UUOKFMHZSA-N
InChi Code: InChI=1S/C9H13N3O6/c10-7(16)4-8(17)12(2-11-4)9-6(15)5(14)3(1-13)18-9/h2-3, 5-6, 9, 13-15, 17H, 1H2, (H2, 10, 16)/t3-, 5-, 6-, 9-/m1/s1
SMILES Code: O=C(C1=C(O)N([CH]2O[CH](CO)[CH](O)[CH]2O)C=N1)N
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