Comparison

Vidarabine (Ara-A)

Item no. V1460-500mg
Manufacturer InvivoChem LLC
CASRN 5536-17-4
Amount 500 mg
Quantity options 10 g 1 g 25 g 2 g 50 g 5 g
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias 5536-17-4
Available
Description
InvivoChem Cat #:V1460CAS #:5536-17-4 Purity >=98%

Description: Vidarabine (Ara-A; Adenine Arabinoside; 9-beta-D-Arabinofuranosyladenine; Arabinofuranosyladenine) is an approved antiviral drug that interfers with the synthesis of viral DNA, and is mainly used to treat HSV and VZV: herpes simplex and varicella zoster viruses. Vidarabine and Acyclovir have a synergistic effect on wild type. Vidarabine is capable of inhibiting acyclovir-resistant/TK-deficient mutants of HSV and VZV, because it is phosphorylated to its active vidarabine–triphosphate form by cellular kinases and is not dependent for its activation on the viral TK.

Description:

References: Antiviral Res. 2006 Nov; 72(2):157-61; Antivir Chem Chemother. 2004 Sep; 15(5):281-5.

References:

Related CAS#: 29984-33-6 (phosphate); 53910-25-1 (Pentostatin); 5536-17-4 (free base); 24356-66-9 (hydrate)

Molecular Weight (MW)
267.24
Formula
C10H13N5O4
CAS No.
5536-17-4 (free);
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Solubility (In vitro)
DMSO: 53 mg/mL (198.3 mM)
Water: 3 mg/mL (11.2 mM)
Ethanol: < 1 mg/mL
Other info

Chemical Name: (2R, 3S, 4S, 5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3, 4-diol

InChi Key: OIRDTQYFTABQOQ-UHTZMRCNSA-N

InChi Code: InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4, 6-7, 10, 16-18H, 1H2, (H2, 11, 12, 13)/t4-, 6-, 7+, 10-/m1/s1

SMILES Code: O[CH]1[CH](N2C=NC3=C(N)N=CN=C23)O[CH](CO)[CH]1O

Synonyms

Adenine Arabinoside; 9-beta-D-Arabinofuranosyladenine; Vira A; Vira-A; ViraA; Ara-A; Ara A; Arabinofuranosyladenine; 9-beta-Arabinofuranosyladenine; Vidarabine.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 mg
Available: In stock
available

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