Comparison

SR 59230A HCl

Item no. V15215-5mg
Manufacturer InvivoChem LLC
CASRN 1135278-41-9
Amount 5 mg
Quantity options 100 mg 10 mg 250 mg 25 mg 50 mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias 1135278-41-9
Available
Description
InvivoChem Cat #:V15215CAS #:1135278-41-9Purity >=98%

Description: SR 59230A HCl is a potent, brain penetrant and selective beta3 adrenoceptor antagonist with IC50 values of 40, 408 and 648 nM for beta3, beta1 and beta2 receptors respectively. SR-59230A was shown to block the hyperthermia produced by MDMA inanimal studies. SR 59230A blocks MDMA-induced hyperthermia, while athigh concentrations it blocks hyperthermia but also increases heat lossthrough an alpha1-AR antagonistic mechanism.

References: Mol Pharmacol. 1996 Jan; 49(1):7-14.; Diabetes Obes Metab. 2012 Oct; 14(10):960-2.

Related CAS: 1135278-41-9 (HCl) 174689-39-5 (free base); 174689-39-5 (oxalate)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 5 mg
Available: In stock
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