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EHT 1864 2HCl

EHT 1864 2HCl

Item no.	V1566-5mg
Manufacturer	InvivoChem LLC
CASRN	754240-09-0
Amount	5 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	754240-09-0
Available
Description	InvivoChem Cat #:V1566CAS #:754240-09-0Purity >=98% Description: EHT 1864 dihydrochloride is a potent and novel Rac family GTPase inhibitor with Kd of 40 nM, 50 nM, 60 nM and 250 nM for Rac1, Rac1b, Rac2 and Rac3, respectively. EHT 1864 attenuates glucose-stimulated insulin secretion in pancreatic beta-cells. EHT 1864 specifically inhibits glucose-induced Rac1 activation and membrane association and associated downstream signaling events culminating in inhibition of GSIS. References: J Biol Chem. 2007 Dec 7; 282(49):35666-78; J Biol Chem. 2005 Nov 11; 280(45):37516-25. Related CAS#: CAS#754240-09-0 (dihydrochloride); 754239-64-0 (free base)
Molecular Weight (MW)	581.47
Formula	C25H29Cl2F3N2O4S
CAS No.	754240-09-0
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 100 mg/mL (172.0 mM)
	Water: 100 mg/mL (172.0 mM)
	Ethanol: < 1 mg/mL
SMILES	O=C1C=C(CN2CCOCC2)OC=C1OCCCCCSC3=CC=NC4=CC(C(F)(F)F)=CC=C34
Synonyms	EHT-1864; EHT1864; EHT 1864 HCl

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5 mg

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