« Back
Home /
ccg-1423

ccg-1423

Item no.	V1567-5mg
Manufacturer	InvivoChem LLC
CASRN	285986-88-1
Amount	5 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	285986-88-1
Available
Description	InvivoChem Cat #: V1567CAS #:285986-88-1Purity >=98% Description: CCG-1423 is a novel, potent and specific small-molecule inhibitor of RhoA signaling pathway, which inhibits SRF-mediated transcription. CCG-1423 displays activity in several in vitro cancer cell functional assays. CCG-1423 potently (< 1 mumol/L) inhibits lysophosphatidic acid-induced DNA synthesis in PC-3 prostate cancer cells, and whereas it inhibits the growth of RhoC-overexpressing melanoma lines (A375M2 and SK-Mel-147) at nanomolar concentrations, it is less active on related lines (A375 and SK-Mel-28) that express lower levels of Rho. References: Mol Cancer Ther. 2007 Aug; 6(8):2249-60; Biochem Biophys Res Commun. 2010 Mar 19; 393(4):877-82.
Molecular Weight (MW)	454.75
Formula	C18H13ClF6N2O3
CAS No.	285986-88-1
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 90 mg/mL (197.9 mM)
	Water: < 1 mg/mL
	Ethanol: 4 mg/mL (8.8 mM)
Other info	Chemical Name: N-((1-((4-chlorophenyl)amino)-1-oxopropan-2-yl)oxy)-3, 5-bis(trifluoromethyl)benzamide InChi Key: DSMXVSGJIDFLKP-UHFFFAOYSA-N InChi Code: InChI=1S/C18H13ClF6N2O3/c1-9(15(28)26-14-4-2-13(19)3-5-14)30-27-16(29)10-6-11(17(20, 21)22)8-12(7-10)18(23, 24)25/h2-9H, 1H3, (H, 26, 28)(H, 27, 29) SMILES Code: O=C(NOC(C)C(NC1=CC=C(Cl)C=C1)=O)C2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2
Synonyms	CCG1423; CCG-1423; CCG 1423

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 5 mg

available

Delivery expected until 9/4/2025

Express Delivery: Save 13 days

Compare

Add to wishlist

Get an offer