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Nocodazole (Oncodazole; R17934)

Nocodazole (Oncodazole; R17934)

Item no.	V1608-10mg
Manufacturer	InvivoChem LLC
CASRN	31430-18-9
Amount	10 mg
Quantity options	100 mg 1 g 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	31430-18-9
Available
Description	InvivoChem Cat #:V1608CAS #:31430-18-9Purity >=98% Description: Nocodazole (Oncodazole; R17934) is a potent and rapidly-reversible inhibitor of microtubule polymerization, also inhibits Abl, Abl(E255K) and Abl(T315I) with IC50 of 0.21 uM, 0.53 uM and 0.64 uM in cell-free assays, respectively. Nocodazole is used as an anti-cancer agent which exerts its effect in cells by interfering with the polymerization of microtubules. Nocodazole induces apoptosis in chronic lymphocytic leukemia cells. It inhibits insulin-stimulated glucose transport. Nocodazole decreases apoptosis in some human colon carcinoma cells. References: ChemMedChem. 2012 Jan 2; 7(1):53-6; Mol Carcinog. 2002 Aug; 34(4):199-210.
Molecular Weight (MW)	301.32
Formula	C14H11N3O3S
CAS No.	31430-18-9
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 7 mg/mL (23.2 mM)
	Water:< 1 mg/mL
	Ethanol: < 1 mg/mL
Solubility (In vivo)	1% DMSO+30% polyethylene glycol+1% Tween 80: 30 mg/mL
Synonyms	Oncodazole; R-17934; R 17934; R17934

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 mg

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