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tlr2-in-c29

tlr2-in-c29

Item no.	V16506-10mg
Manufacturer	InvivoChem LLC
CASRN	363600-92-4
Amount	10mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V16506CAS #:363600-92-4Purity >=98% Description: TLR2-IN-C29 is an inhibitor of TLR2/1 and TLR2/6 signaling. It is induced by synthetic and bacterial TLR2 agonists in human HEK-TLR2 and THP-1 cells, but only TLR2/1 signaling in murine macrophages. References: Mistry P, Laird MH, Schwarz RS, Greene S, Dyson T, Snyder GA, Xiao TS, Chauhan J, Fletcher S, Toshchakov VY, MacKerell AD Jr, Vogel SN. Inhibition of TLR2 signaling by small molecule inhibitors targeting a pocket within the TLR2 TIR domain. Proc Natl Acad Sci U S A. 2015 Apr 28; 112(17):5455-60. doi: 10.1073/pnas.1422576112. Epub 2015 Apr 13. PubMed PMID: 25870276; PubMed Central PMCID: PMC4418912.

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Amount: 10mg

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