Comparison

Dronedarone HCl (SR33589)

Item no. V1670-25mg
Manufacturer InvivoChem LLC
CASRN 141625-93-6
Amount 25 mg
Quantity options 100 mg 1 g 250 mg 500 mg 50 mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias 141625-93-6
Available
Description
InvivoChem Cat #:V1670CAS #:141625-93-6 Purity >=98%

Description: Dronedarone (slao known as SR33589) HCl is a non-iodinated amiodarone analogue which has been used as an effective and promising treatment for Atrial fibrillation (AF). Dronedarone works as a multichannel blocker targeting potassium channel, sodium channel and calcium channel. In vitro, dronedarone has been demonstrated to inhibit muscarinic acetylcholine receptor-operated K+ current IK(ACh) induced by carbachol or GTP-gamma-S with IC50 values of 10nm and< 100nm, respectively, in cells isolated from guinea pig atria.

References: J Cardiovasc Pharmacol. 2000; 36(6):802-5; Br J Pharmacol. 2001; 133(5):625-34.

Molecular Weight (MW)
593.22
Formula
C31H44N2O5S.HCl
CAS No.
141625-93-6
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Solubility (In vitro)
DMSO: 80 mg/mL (134.9 mM)
Water: < 1 mg/mL
Ethanol: 40 mg/mL (67.4 mM)
Other info

Chemical Name: N-[2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-1-benzofuran-5-yl]methanesulfonamide; hydrochloride

InChi Key: DWKVCQXJYURSIQ-UHFFFAOYSA-N

InChi Code: InChI=1S/C31H44N2O5S.ClH/c1-5-8-12-29-30(27-23-25(32-39(4, 35)36)15-18-28(27)38-29)31(34)24-13-16-26(17-14-24)37-22-11-21-33(19-9-6-2)20-10-7-3; /h13-18, 23, 32H, 5-12, 19-22H2, 1-4H3; 1H

SMILES Code: CCCCC1=C(C2=C(O1)C=CC(=C2)NS(=O)(=O)C)C(=O)C3=CC=C(C=C3)OCCCN(CCCC)CCCC.Cl

Synonyms
SR-33589; SR 33589; SR33589; Dronedarone Hydrochloride; 4CH-007232; D4689; W3083; D03914; S-7529; MCULE-2160502046; RL01735; RTC-070901; AK-72887; BC201083; BR-72887; HY-75839; KB-76727; AB2000517; ST2413542; Dronedarone HCl; UNII-FA36DV299Q

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 25 mg
Available: In stock
available

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