o4i2

Item no.	V1695-5mg
Manufacturer	InvivoChem LLC
CASRN	165682-93-9
Amount	5 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	165682-93-9
Available
Description	InvivoChem Cat #:V1695CAS #:165682-93-9Purity >=98% Description: O4I2 is a novel and potent Oct3/4 inducer, which is suitable for iPSC generation. O4I2 shows high activity in enforcing Oct3/4 expression. O4I2 activates Oct3/4 on the transcriptional and translational level in human fibroblasts. O4I2 promotes the expression of pluripotency-associated genes as analyzed by qRT-PCR in human neonatal foreskin fibroblasts (HFFs). O4I2 markedly stimulates Oct3/4 even at 5 uM after 72 h treatment on the translational level. References: J Med Chem. 2015 Aug 13; 58(15):5742-50.
Molecular Weight (MW)	282.75
Formula	C12H11ClN2O2S
CAS No.	165682-93-9
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 56 mg/mL (198.1 mM)
	Water: < 1 mg/mL
	Ethanol: 20 mg/mL (70.7 mM)
Other info	Chemical Name: ethyl 2-((4-chlorophenyl)amino)thiazole-4-carboxylate InChi Key: ULUBAPWNHROTEU-UHFFFAOYSA-N InChi Code: InChI=1S/C12H11ClN2O2S/c1-2-17-11(16)10-7-18-12(15-10)14-9-5-3-8(13)4-6-9/h3-7H, 2H2, 1H3, (H, 14, 15) SMILES Code: O=C(C1=CSC(NC2=CC=C(Cl)C=C2)=N1)OCC
Synonyms	O4I2; O-4I2; O4I-2

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