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flutamide

flutamide

Item no.	V1764-500mg
Manufacturer	InvivoChem LLC
CASRN	13311-84-7
Amount	500 mg
Quantity options	100 g 10 g 1 g 2 g 5 g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	13311-84-7
Available
Description	InvivoChem Cat #:V1764CAS #:13311-84-7Purity >=98% Description: Flutamide (also known as SCH13521), a toluidine derivative, is a potent non-steroidal antiandrogen drug with an active metablolite that binds to androgen receptor with Ki value of 55 nM, and is mainly used for the treatment of prostate cancer. Flutamideis a toluidine derivative and nonsteroidal antiandrogen that is structurally related to bicalutamide and nilutamide. Flutamide and the more active metabolite 2-hydroxyflutamide competitively block dihydrotestosterone binding at androgen receptors, forming inactive complexes which cannot translocate into the cell nucleus. References: Mol Cell Endocrinol. 1986 Mar; 44(3):261-70; J Steroid Biochem. 1988 Jun; 29(6):691-8. Related CAS#: 52806-53-8 (2-Hydroxyflutamide)
Molecular Weight (MW)	276.21
Formula	C11H11F3N2O3
CAS No.	13311-84-7
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 55 mg/mL (199.1 mM)
	Water: < 1 mg/mL
	Ethanol: 55 mg/mL (199.1 mM)
Other info	Chemical Name: N-(4-nitro-3-(trifluoromethyl)phenyl)isobutyramide InChi Key: MKXKFYHWDHIYRV-UHFFFAOYSA-N InChi Code: InChI=1S/C11H11F3N2O3/c1-6(2)10(17)15-7-3-4-9(16(18)19)8(5-7)11(12, 13)14/h3-6H, 1-2H3, (H, 15, 17) SMILES Code: CC(C)C(NC1=CC=C([N+]([O-])=O)C(C(F)(F)F)=C1)=O
Synonyms	SCH-13521; SCH13521; SCH-13521; SCH 13521; trade names: Flucinom; Flugerel; Niftolid; Eulexin; Apimid; Chimax; Drogenil; Euflex; Eulexine; Flucinome; Fluken; Flulem; Flutabene; Flutacan; FlutaGry; Flutamex; Flutamin; Flutan; Flutaplex; Fugerel; Grisetin; Oncosal; Profamid; Prostacur; Prostadirex; Prostica; Prostogenat; Tafenil; Tecnoflut; Testotard. FLUT.

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Amount: 500 mg

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