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emtricitabine

emtricitabine

Item no.	V1813-100mg
Manufacturer	InvivoChem LLC
CASRN	143491-57-0
Amount	100mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	143491-57-0
Available
Description	InvivoChem Cat #:V1813CAS #:143491-57-0 Purity >=98% Description: Emtricitabine (BW1592; FTC; Coviracil; Emtriva; Racivir) is a potent nucleoside reverse transcriptase inhibitor (NRTI) with an EC50 of 0.01 uM and has been used for the treatment of both human immunodeficiency virus (HIV) and hepatitis B virus. Emtricitabine is structurally similar to Lamivudine. It is effective at targeting HIV and HBV viruses since these viruses replicate in a reverse transcriptase manner. Studies indicate that the structure of Emtricitabine, specifically the unnatural beta-L structural configuration produce greater antiviral effects in vitro on HIV and HBV than other antiviral agents. nucleoside reverse transcriptase inhibitor References: Antivir Ther. 2007; 12(7):1075-85; Antivir Ther. 2006; 11(3):377-84. Related CAS#:152128-77-3 (Emtricitabine S-oxide); 160707-69-7 Apricitabine, (-)-BCH-10652; (-)-dOTC; AVX-754; BCH-10618; SPD-754; 1011529-10-4 (Azvudine; FNC; RO-0622; RO 0622; RO062); 634907-30-5 (OBP 601; BMS-986001; BMS 986001; BMS986001; festinavir; 4?-Ed4T; Censavudine); 147221-93-0 (Delavirdine mesylate) 136817-59-9 (Delavirdine free base); 181785-84-2 (Elvucitabine)
Molecular Weight (MW)	247.25
Formula	C8H10FN3O3S
CAS No.	143491-57-0
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 49 mg/mL (198.2 mM)
	Water: 49 mg/mL (198.2 mM)
	Ethanol: 9 mg/mL (36.4 mM)
Other info	Chemical Name: 4-amino-5-fluoro-1-[(2R, 5S)-2-(hydroxymethyl)-1, 3-oxathiolan-5-yl]pyrimidin-2-one InChi Key: XQSPYNMVSIKCOC-NTSWFWBYSA-N InChi Code: InChI=1S/C8H10FN3O3S/c9-4-1-12(8(14)11-7(4)10)5-3-16-6(2-13)15-5/h1, 5-6, 13H, 2-3H2, (H2, 10, 11, 14)/t5-, 6+/m0/s1 SMILES Code: C1[CH](O[CH](S1)CO)N2C=C(C(=NC2=O)N)F
Synonyms	BW-1592; BW1592; BW 1592; trade names: Coviracil; Emtriva; Racivir; (-)-FTC; W-201247; W-201248; E1007; 24229-EP2298783A1; 24229-EP2314590A1; AB01275429-01; 3B2-0188

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Amount: 100mg

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