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8-Bromo-cAMP

8-Bromo-cAMP

Item no.	V1847-5mg
Manufacturer	InvivoChem LLC
CASRN	76939-46-3
Amount	5 mg
Quantity options	100 mg 10 mg 1 g 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	76939-46-3
Available
Description	InvivoChem Cat #:V1847CAS #:76939-46-3Purity >=98% Description: 8-Bromo-cAMP is a potent and cell permeable cyclic AMP (cAMP) analog and a PKA activator. 8-Bromo-cAMP increased the cellular content of mRNA encoding the hCG a- and beta-subunits and prevented the increase in fibronectin mRNA. This is determined by blot hybridization analysis using specific cDNA probes. 8-Bromo-cAMP also induced phosphorylation of Erk1, 2 in AML193 cells. 8-Bromo-cAMP is an agent in AML193 cells and activates Erk1, 2 , this condition happens does not accompanied by the involvement of Shc phosphorylation. References: Stem Cell Rev. 2011 Jun; 7(2):331-41; Am J Physiol Lung Cell Mol Physiol. 2014 Oct 15; 307(8):L643-51.
Molecular Weight (MW)	430.08
Formula	C10H10BrN5NaO6P
CAS No.	76939-46-3
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 80 mg/mL (186.01 mM)
	Water: < 1 mg/mL
	Ethanol: 35 mg/mL (81.38 mM)
Other info	Chemical Name: sodium (4aR, 6R, 7R, 7aS)-6-(6-amino-8-bromo-9H-purin-9-yl)-7-hydroxytetrahydro-4H-furo[3, 2-d][1, 3, 2]dioxaphosphinin-2-olate 2-oxide InChi Key: DMRMZQATXPQOTP-GWTDSMLYSA-M InChi Code: InChI=1S/C10H11BrN5O6P.Na/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-5(17)6-3(21-9)1-20-23(18, 19)22-6; /h2-3, 5-6, 9, 17H, 1H2, (H, 18, 19)(H2, 12, 13, 14); /q; +1/p-1/t3-, 5-, 6-, 9-; /m1./s1 SMILES Code: O[CH]1[CH](O[CH]2[CH]1OP(OC2)([O-])=O)N3C(Br)=NC4=C3N=CN=C4N.[Na+]
Synonyms	8 Br cAMP Na; 8BrcAMP sodium; 8-Br-cAMP Na

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Amount: 5 mg

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