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Description: D-Luciferin is a popular and cell-permeable bioluminescent substrate of luciferase in the presence of ATP with a Km of approximately 2 uM, it is used in luciferase-based bioluminescence imaging and cell-based high-throughput screening applications. D-luciferin could emit lights upon oxidative decarboxylation in the presence of ATP. D-luciferin provides a bioluminescent signal for in vivo and in vitro detection of cellular ATP levels. D-Luciferin chould be used to assay the expression of the luciferase gene linked to a promoter of interest. Alternatively, D-luciferin and luciferase can be used to assess ATP availability in cellular or biochemical assays. D-luciferin could be administrated intravenously or intraperitonealy.
References: J Clin Chem Clin Biochem. 1987 Aug; 25(8):511-4; J Immunother Cancer. 2015 May 19; 3:16.
Chemical Name: (4S)-2-(6-hydroxy-1, 3-benzothiazol-2-yl)-4, 5-dihydrothiazole-4-carboxylic acid
InChi Key: BJGNCJDXODQBOB-SSDOTTSWSA-N
InChi Code: InChI=1S/C11H8N2O3S2/c14-5-1-2-6-8(3-5)18-10(12-6)9-13-7(4-17-9)11(15)16/h1-3, 7, 14H, 4H2, (H, 15, 16)/t7-/m1/s1
SMILES Code: O=C([CH]1N=C(C2=NC3=CC=C(O)C=C3S2)SC1)O
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.
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