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sodium-tauroursodeoxycholate-tudc

sodium-tauroursodeoxycholate-tudc

Item no.	V1890-1g
Manufacturer	InvivoChem LLC
CASRN	35807-85-3
Amount	1g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1890CAS #:35807-85-3 Purity >=98% Description: Sodium Tauroursodeoxycholate (TUDC) is a water soluble bile salt, which is used for the treatment of gallstones and liver cirrhosis. In vitro, Tauroursodeoxycholate shows protective and reversing effects on 17betaEG-induced impairment of the cVA-of-CLF. In Mz-ChA-1 cholangiocarcinoma cells, Tauroursodeoxycholate inhibits cell growth via Ca2+-, PKC-, and MAPK-dependent pathways. In isolated rat hepatocytes, Tauroursodeoxycholate inhibits bile acid-Induced Apoptosis via a beta1-integrin-mediated formation of cAMP. References: J Hepatol. 2001 Feb; 34(2):184-91; Eur J Pharmacol. 2001 Jun 1; 421(1):55-60; Am J Physiol Gastrointest Liver Physiol. 2004 Jun; 286(6):G973-82.
Molecular Weight (MW)	521.69
Formula	C26H44NNaO6S
CAS No.	35807-85-3
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 100 mg/mL (191.7 mM)
	Water: 100 mg/mL (191.7 mM)
	Ethanol: 71 mg/mL (136.1 mM)
SMILES	C[CH](CCC(NCCS(=O)([O-])=O)=O)[CH]1CC[C]2([H])[C]3([H])[CH](O)C[C]4([H])C[CH](O)CC[C]4(C)[C]3([H])CC[C]12C.[Na+]
Synonyms	TUDC; Sodium tauroursodeoxycholate; Tauroursodeoxycholic acid sodium salt

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