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BAPTA-AM

BAPTA-AM

Item no.	V1933-5mg
Manufacturer	InvivoChem LLC
CASRN	126150-97-8
Amount	5 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	126150-97-8
Available
Description	InvivoChem Cat #:V1933CAS #:126150-97-8Purity >=98% Description: BAPTA-AM is a selective, membrane-permeable and intracellular calcium chelator. In the human leukemia cell lines HL-60 and U937, BAPTA/AM (10 uM) induced internucleosomal DNA cleavage and classic apoptotic morphology. Also, BAPTA/AM increased Ca2+ in intracellular and downregulated c-jun. In bovine chromaffin cells, APTA-AM (50 uM) rapidly and reversibly inhibited Ca2+-activated K+ (I(KCa)) and voltage-gated K+ (I(K)) by 50%. In HEK 293 cells, BAPTA-AM inhibited hERG (Kv11.1), hKv1.3 and hKv1.5 channels with IC50 values of 1.3, 1.45 and 1.23 uM respectively in a concentration dependent way. References: Prog Neuropsychopharmacol Biol Psychiatry. 2001 Nov; 25(8):1641-59; Biochem Pharmacol.
Molecular Weight (MW)	764.68
Formula	C34H40N2O18
CAS No.	126150-97-8
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 20 mg/mL (26.2 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Other info	Chemical Name: Acetyloxymethyl 2-[N-[2-(acetyloxymethoxy)-2-oxoethyl]-2-[2-[2-[bis[2-(acetyloxymethoxy)-2-oxoethyl]amino]phenoxy]ethoxy]anilino]acetate SMILES Code: O=C(OCOC(C)=O)CN(CC(OCOC(C)=O)=O)C1=CC=CC=C1OCCOC2=CC=CC=C2N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O
Synonyms	BAPTA-AM; BAPTA AM; BAPTA/AM

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Amount: 5 mg

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