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OAC1 (BAS 00287861)

OAC1 (BAS 00287861)

Item no.	V1955-5mg
Manufacturer	InvivoChem LLC
CASRN	300586-90-7
Amount	5 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	300586-90-7
Available
Description	InvivoChem Cat #:V1955CAS #:300586-90-7Purity >=98% Description: OAC-1 (also known as BAS 00287861) is an Oct-4 (Octamer-binding transcription factor-4) activator which enhances and accelerates iPSC reprogramming in the presence of 4F (Oct-4, Sox-2, c-Myc and GKLF) by ca.20-fold (relative to 4F by itself). OAC-1 upregulates mRNA expression of Oct-4, Sox-2 and Nanog, as well as Tet1. It has shown no effects, however, on the p53-p21 pathway or Wnt-beta-catenin signaling. In luciferase reporter assays, OAC1 activated both human Oct4 and Nanog promoter-driven luciferase reporter genes. References: Proc Natl Acad Sci U S A. 2012 Dec 18; 109(51):20853-8.
Molecular Weight (MW)	237.26
Formula	C14H11N3O
CAS No.	300586-90-7
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 47 mg/mL (198.1 mM)
	Water: < 1 mg/mL
	Ethanol: 21 mg/mL (88.5 mM)
Other info	Chemical Name: N-(1H-pyrrolo[2, 3-c]pyridin-5-yl)benzamide InChi Key: HWJRIFZDXJKJJN-UHFFFAOYSA-N InChi Code: InChI=1S/C14H11N3O/c18-14(10-4-2-1-3-5-10)17-13-8-11-6-7-15-12(11)9-16-13/h1-9, 15H, (H, 16, 17, 18) SMILES Code: O=C(NC1=CC2=C(NC=C2)C=N1)C3=CC=CC=C3
Synonyms	BAS-00287861; BAS00287861; BAS 00287861; OAC 1; OAC1; OAC-1

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Amount: 5 mg

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