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Cefoselis Sulfate (FK-037)

Cefoselis Sulfate (FK-037)

Item no.	V2035-5mg
Manufacturer	InvivoChem LLC
CASRN	122841-12-7
Amount	5 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	122841-12-7
Available
Description	InvivoChem Cat #:V2035CAS #:122841-12-7 Purity >=98% Description: Cefoselis (also known as FK 037 Sulfate) is a widely used beta-lactam antibiotic of the cephalosporin class. Cefoselis inhibits GABA-induced currents in a concentration-dependent manner with IC50 of 185 mM. Cefoselis possesses a superior antistaphylococcal activity on MSSA isolates to both other compounds being however equal active to Cefepime and Cefpirome on multiresistant enterobacteriaceae. Cefoselis is dose-dependently appeared in brain extracellular fluid in proportion to its blood level. Cefoselis, a new parenteral cephalosporin, is active against clinical isolates of both gram-positive and gram-negative aerobic bacteria. References: Br J Pharmacol. 2002 Jan; 135(2):427-32; J Neural Transm (Vienna). 2004 Dec; 111(12):1523-35.
Molecular Weight (MW)	620.64
Formula	C19H22N8O6S2.H2SO4
CAS No.	122841-12-7
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 3 mg/mL (4.8 mM)
	Water: 5 mg/mL (8.0 mM)
	Ethanol: < 1 mg/mL
Other info	Chemical Name: (6R, 7R)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-((2-(2-hydroxyethyl)-3-imino-2, 3-dihydro-1H-pyrazol-1-yl)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid compound with sulfuric acid (1:1) InChi Key: LZOLCSVRFKCSEM-ZQCAECPKSA-N InChi Code: InChI=1S/C19H22N8O6S2.H2O4S/c1-33-24-12(10-8-35-19(21)22-10)15(29)23-13-16(30)27-14(18(31)32)9(7-34-17(13)27)6-25-3-2-11(20)26(25)4-5-28; 1-5(2, 3)4/h2-3, 8, 13, 17, 20, 28H, 4-7H2, 1H3, (H2, 21, 22)(H, 23, 29)(H, 31, 32); (H2, 1, 2, 3, 4)/b20-11?, 24-12-; /t13-, 17-; /m1./s1 SMILES Code: O=C(C(N12)=C(CN3N(CCO)C(C=C3)=N)CS[C]2([H])[CH](NC(/C(C4=CSC(N)=N4)=N\OC)=O)C1=O)O.O=S(O)(O)=O
Synonyms	FK 037 Sulfate; FK037; FK-037

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Amount: 5 mg

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